This episode reveals how Randy and Howard met and became friends.
The episode title is a reference to the 1989 film When Harry Met Sally.
It is confirmed that Randy and Howard met in a bath together as 3 years old, and it was mentioned in "So U Think U Can Stank."
Randy reveals that Howard's story of the time when they met the Ninja of '05 is not actually the story of how Howard and Randy themselves first met, as Howard pretends; however, the story is substantially true in other respects.
Marci gets stanked in this episode. This episode also reveals that Marci is the first monster Randy ever distanked.
Another past ninja, the Ninja of '05, makes a second appearance. The first one had been shown as a doodle in "Ninjaception."
It is revealed that Marci used to run a daycare center.
The character in Doug's drawing might be an allusion to Courage from the cartoon Courage the Cowardly Dog.
Stevens is revealed to be left-handed.
Randy's amusement by the Ninja of '05's puns shows that he probably got his punny humor from him.